成分股Erasca收跌10.21%，Summit Therapeutics Plc.跌10.17%，Nautilus Biotechnology跌9.58%，杰龙跌9.13%，Third Harmonic Bio也跌8.83%，Vanda Pharmaceuticals则收涨3.04%，bluebird bio涨3.98%，Vera Therapeutics涨4.16%，Ventyx Biosciences涨6.96%。